Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1983-6-10
pubmed:databankReference
pubmed:abstractText
We have determined the nucleotide sequence in the U3-R regions of the long terminal repeat (LTR) associated with NFS-Th-1 xenotropic murine leukemia virus (MuLV) DNA and the LTR components of five endogenous proviruses cloned from BALB/c mouse chromosomal DNA. The five endogenous MuLV LTRs contained the regulatory signals thought to be important in viral transcription, such as "TATAA" and CCAAT-like boxes. A unique feature in four of the endogenous LTRs was the presence of a highly conserved 190-base-pair (bp) insert bounded by 6-bp direct repeats located 48 bp upstream from the C-C-A-A-T sequence. This segment was absent from LTRs associated with ecotropic, xenotropic, or mink cell focus-forming (MCF) MuLV proviruses. All five endogenous LTR segments also contained a 14-bp duplication of a sequence located near the 5' end of the first component of the long (greater than 72-bp) direct repeat of ecotropic and MCF MuLV LTRs. An evolutionary scheme relating LTRs associated with endogenous MuLV proviral DNAs to those found in ecotropic or xenotropic proviruses is presented. Nucleotide sequence analysis also suggested that the U3 region of the MCF247 MuLV LTR is derived from an NFS xenotropic related MuLV.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/6302701-271968, http://linkedlifedata.com/resource/pubmed/commentcorrection/6302701-6177038, http://linkedlifedata.com/resource/pubmed/commentcorrection/6302701-6245092, http://linkedlifedata.com/resource/pubmed/commentcorrection/6302701-6250038, http://linkedlifedata.com/resource/pubmed/commentcorrection/6302701-6251455, http://linkedlifedata.com/resource/pubmed/commentcorrection/6302701-6251969, http://linkedlifedata.com/resource/pubmed/commentcorrection/6302701-6253201, http://linkedlifedata.com/resource/pubmed/commentcorrection/6302701-6254003, http://linkedlifedata.com/resource/pubmed/commentcorrection/6302701-6254069, http://linkedlifedata.com/resource/pubmed/commentcorrection/6302701-6256079, http://linkedlifedata.com/resource/pubmed/commentcorrection/6302701-6256658, http://linkedlifedata.com/resource/pubmed/commentcorrection/6302701-6260371, http://linkedlifedata.com/resource/pubmed/commentcorrection/6302701-6260957, http://linkedlifedata.com/resource/pubmed/commentcorrection/6302701-6270353, http://linkedlifedata.com/resource/pubmed/commentcorrection/6302701-6276750, http://linkedlifedata.com/resource/pubmed/commentcorrection/6302701-6281459, http://linkedlifedata.com/resource/pubmed/commentcorrection/6302701-6281466, http://linkedlifedata.com/resource/pubmed/commentcorrection/6302701-6283115, http://linkedlifedata.com/resource/pubmed/commentcorrection/6302701-6287025, http://linkedlifedata.com/resource/pubmed/commentcorrection/6302701-6292522, http://linkedlifedata.com/resource/pubmed/commentcorrection/6302701-6292901, http://linkedlifedata.com/resource/pubmed/commentcorrection/6302701-6296437, http://linkedlifedata.com/resource/pubmed/commentcorrection/6302701-6298457, http://linkedlifedata.com/resource/pubmed/commentcorrection/6302701-657274, http://linkedlifedata.com/resource/pubmed/commentcorrection/6302701-7326747
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0027-8424
pubmed:author
pubmed:issnType
Print
pubmed:volume
80
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2699-703
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Endogenous murine leukemia proviral long terminal repeats contain a unique 190-base-pair insert.
pubmed:publicationType
Journal Article