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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1983-5-27
|
| pubmed:abstractText |
After secondary immunizations of rhesus(D)-negative male volunteers with Rh(D)-positive red cells, changes were found in the in vitro transformation and antibody-dependent cell-mediated cytotoxicity (ADCC) capacities of the volunteers' lymphocytes. Responders, who produced anti-D, showed marked depressions of ADCC which were not found in non-responders. Responders and non-responders in general showed similar changes in lymphocyte transformation. The relationships between altered lymphocyte functions following immunization, immunoregulatory activity and responsiveness to the Rh(D) antigen are discussed.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0007-1048
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
53
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
629-40
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:6299324-Antibody-Dependent Cell Cytotoxicity,
pubmed-meshheading:6299324-Humans,
pubmed-meshheading:6299324-Immunization, Secondary,
pubmed-meshheading:6299324-Immunoglobulins,
pubmed-meshheading:6299324-Lymphocyte Activation,
pubmed-meshheading:6299324-Lymphocytes,
pubmed-meshheading:6299324-Male,
pubmed-meshheading:6299324-Prospective Studies,
pubmed-meshheading:6299324-Rh-Hr Blood-Group System,
pubmed-meshheading:6299324-Rho(D) Immune Globulin,
pubmed-meshheading:6299324-Time Factors
|
| pubmed:year |
1983
|
| pubmed:articleTitle |
Rhesus immunization in male volunteers: changes in lymphocyte functions following secondary immunizations in anti-D responders and non-responders.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|