Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1983-4-7
pubmed:abstractText
A prospective, randomized, double-masked study was conducted to compare the efficacy of steroid/antibiotic treatment to placebo in reducing postoperative ocular inflammation. Patients undergoing planned extracapsular cataract extraction with intraocular lens implantation were treated with either placebo or a combination product containing dexamethasone, neomycin, and polymyxin B for three days prior to surgery and three weeks following surgery. Five of thirteen (38%) patients treated with placebo developed significant iritis postoperatively, while none of ten (0%) patients treated with the combination product developed excessive inflammation (P = 0.027). Two patients treated with the steroid/antibiotic combination product experienced a broken suture postoperatively followed by iris prolapse, as compared to none in the placebo group (P greater than 0.10). More types and significant numbers of bacteria were isolated from the eyes of the placebo-treatment group after therapy than were found in the steroid/antibiotic-treatment group.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0003-4886
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
24-8
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Use of steroid/antibiotic prophylaxis in intraocular lens implantation: a double-masked study v placebo.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Randomized Controlled Trial