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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5881
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pubmed:dateCreated |
1982-10-29
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pubmed:abstractText |
Members of three distinct classes of animal virus have been associated with naturally occurring neoplasias in man: Epstein--Barr virus (EBV), a DNA virus belonging to herpesvirus group, papillomavirus, and a novel human RNA (retro) virus, human T-cell leukemia virus or adult T-cell leukaemia (ATL) virus. We have established seven continuous cell lines from ATL patients and 0.1-7% of these cells consistently express ATL-specific antigens (ATLA). EBV-associated nuclear antigen (EBNA) is also found in more than 90% of these cells. We have cloned cells from two of these lines and show here that both ATLA and EBNA were present in the same B-cell clone carrying surface immunoglobulin (sIg).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0028-0836
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
23
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pubmed:volume |
299
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
367-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6287295-Adult,
pubmed-meshheading:6287295-Aged,
pubmed-meshheading:6287295-Antibodies, Monoclonal,
pubmed-meshheading:6287295-Antigens, Viral,
pubmed-meshheading:6287295-Cell Line,
pubmed-meshheading:6287295-Female,
pubmed-meshheading:6287295-Herpesvirus 4, Human,
pubmed-meshheading:6287295-Humans,
pubmed-meshheading:6287295-Leukemia,
pubmed-meshheading:6287295-Male,
pubmed-meshheading:6287295-Middle Aged,
pubmed-meshheading:6287295-Retroviridae,
pubmed-meshheading:6287295-T-Lymphocytes
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pubmed:year |
1982
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pubmed:articleTitle |
Unique cell lines harbouring both Epstein-Barr virus and adult T-cell leukaemia virus, established from leukaemia patients.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|