Linked Life Data

6285855

Source:http://linkedlifedata.com/resource/pubmed/id/6285855

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1982-9-17
pubmed:abstractText
Clinical evaluation of drugs is usually carried out in young adult subjects or patients and the data obtained is extrapolated to other drug users, e.g., the very old. Similarly, preclinical toxicity testing is invariably done in young animals. However, the main brunt of adverse drug reactions is borne by the elderly age group. Also many determinants of drug response - pathophysiology, pharmacokinetics and pharmacodynamics are different in the elderly. It is important to evaluate drug response both wanted and unwanted with this population in mind. Thus, it is appropriate that clinical effects be assessed in elderly populations if the drug is intended for use in this group.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0171-9750
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
59-63
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Toxicity testing in relation to aging.
pubmed:publicationType
Journal Article