Linked Life Data

6278838

Source:http://linkedlifedata.com/resource/pubmed/id/6278838

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1982-5-21
pubmed:abstractText
The splake, a popular game fish, is a crossbreed which must be reared in nurseries. The fish are marked under anesthesia for later study. We analyze the effect of a common anesthetic, tricaine (MS-222), on the metabolism of foreign compounds in the liver and duodenum of the splake. In the liver and to some extent in the duodenum, aryl hydrocarbon hydroxylase and epoxide hydrase activities were reduced during treatments. The ethoxycoumarin O-deethylase activities were not affected in either the liver or duodenum. Tricaine significantly decreased the hepatic UDP-glucuronosyltransferase activity. The decrease was greater when the aglycone used was p-nitrophenol than with methylumbelliferone. A similar effect was also found after trypsin treatment of the microsomes. No significant decrease in the UDP-glucuronosyltransferase activity was detected in the duodenal mucosa. This was the case when both p-nitrophenol and methylumbelliferone were used as aglycones.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0001-6683
pubmed:author
pubmed:issnType
Print
pubmed:volume
49
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
92-7
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Tricaine (MS-222) induced modification on the metabolism of foreign compounds in the liver and duodenal mucosa of the splake (Salvelinus fontinalis X Salvelinus namaycush).
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't