Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1982-5-27
|
pubmed:abstractText |
Na+, K+ -ATPase activity was measured in red blood cells from 20 nondiabetic euthyroid male Pima Indians with varying degrees of obesity; their body mass indices ranged from 22-60 kg/m2. The na+, K+ -ATPase, measured both by 86Rb uptake in intact cells and ATP hydrolysis by purified membranes, was inversely correlated with body mass index (r = -0.62; P less than 0.005 and r = -0.75; P less than 0.0001, respectively). These results confirm that obesity is associated with decreased Na+, K+ -ATPase in intact red blood cells, and provide the first demonstration of a reduced sodium pump in isolated red cell membrane preparations from obese men.
|
pubmed:grant | |
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0021-972X
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
54
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
721-4
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:6277981-Adenosine Triphosphate,
pubmed-meshheading:6277981-Adult,
pubmed-meshheading:6277981-Arizona,
pubmed-meshheading:6277981-Body Composition,
pubmed-meshheading:6277981-Erythrocytes,
pubmed-meshheading:6277981-Humans,
pubmed-meshheading:6277981-Indians, North American,
pubmed-meshheading:6277981-Male,
pubmed-meshheading:6277981-Membrane Proteins,
pubmed-meshheading:6277981-Middle Aged,
pubmed-meshheading:6277981-Obesity,
pubmed-meshheading:6277981-Rubidium,
pubmed-meshheading:6277981-Sodium-Potassium-Exchanging ATPase
|
pubmed:year |
1982
|
pubmed:articleTitle |
Reduced Na+, K+ -ATPase activity in intact red cells and isolated membranes from obese man.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|