Linked Life Data

6276014

Source:http://linkedlifedata.com/resource/pubmed/id/6276014

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3 Pt 1
pubmed:dateCreated
1982-4-12
pubmed:abstractText
The rRNA genes of Xenopus blood cells are heavily methylated, but there are two regions in the spacer that frequently contain unmethylated CpG. The undermethylated regions coincide with two regions containing a 60 nucleotide tandemly repeated sequence, and they are present in all somatic tissues that we have tested. Sperm rDNA, by contrast, is fully methylated at these sites in the spacer, and indirect evidence suggests that this may also be the case in oocytes. Loss of methyl groups occurs progressively over the first 20 hr of development, the same period in which embryonic rRNA synthesis initiates and increases in rate.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0092-8674
pubmed:author
pubmed:issnType
Print
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
381-90
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Loss of rDNA methylation accompanies the onset of ribosomal gene activity in early development of X. laevis.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't