Linked Life Data

6274730

Source:http://linkedlifedata.com/resource/pubmed/id/6274730

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1982-3-26
pubmed:abstractText
We studied the influence of morphine on intestinal secretion induced by three different secretogogues in an attempt to elucidate the mechanism for its antisecretory activity. In rabbit ileal mucosa in vitro morphine (10(-4) M) did not influence the electrical response to the subsequent administration of prostaglandin E2 or of acetylcholine but did inhibit the net secretion of chloride provoked by both agents and prevented the reduction of sodium adsorption induced by the prostaglandin. Morphine reduced the peak electrical response to cholera toxin and reduced toxin-induced net chloride secretion. The modes of action of morphine appeared to be by both enhancing adsorption, as it does in control, nonsecreting mucosa, and by inhibiting secretogogue activity.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0016-5085
pubmed:author
pubmed:issnType
Print
pubmed:volume
82
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
243-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Studies of the antisecretory activity of morphine in rabbit ileum in vitro.
pubmed:publicationType
Journal Article, In Vitro, Research Support, Non-U.S. Gov't