Linked Life Data

6263407

Source:http://linkedlifedata.com/resource/pubmed/id/6263407

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1981-8-20
pubmed:abstractText
The effects of stimulating alpha-adrenergic receptors in the iris of neonatal rats (up to 30 days of age) whose superior cervical ganglion (SCG) has been decentralized or extirpated 3 days after birth were investigated by measuring changes in pupil diameter. The responses of these experimental animals were compared with those of normal animals of similar age. Alpha-adrenergic stimulation was effected by topical application of noradrenaline (NA) after blockade of beta-adrenoceptors with dichlorisoproterenol and cholinoceptors with atropine. The results reveal that although decentralization of the SCG depletes the NA content of the ipsilateral iris as demonstrated by radio-chemical assay and formaldehyde-induced fluorescence, it does not affect the development of alpha-adrenoceptor responsiveness. Even the more severe disruption of the innervation caused by extirpation of the SCG did not affect the responsiveness of the ipsilateral iris.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0006-8993
pubmed:author
pubmed:issnType
Print
pubmed:day
25
pubmed:volume
213
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
119-26
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Differentiation of alpha-adrenergic responsiveness in the neonatal rat iris after decentralization or extirpation of the superior cervical ganglion.
pubmed:publicationType
Journal Article