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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4499
|
| pubmed:dateCreated |
1981-7-9
|
| pubmed:abstractText |
Spike electrogenesis, local depolarizing and hyperpolarizing responses, spontaneous rhythmic firing, and alternating resting potentials were measured in cells from a continuously cultured small cell carcinoma of the lung. Spike generation was blocked by MnCl2. In view of this evidence for calcium-spike electrogenesis and previous evidence of secretory activity in these cells, this cell line (DMS 53) can provide a model for the study of excitation-secretion behavior in human neoplastic cells.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0036-8075
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
5
|
| pubmed:volume |
212
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1155-7
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:6262914-Action Potentials,
pubmed-meshheading:6262914-Calcium,
pubmed-meshheading:6262914-Carcinoma, Small Cell,
pubmed-meshheading:6262914-Cells, Cultured,
pubmed-meshheading:6262914-Electric Conductivity,
pubmed-meshheading:6262914-Humans,
pubmed-meshheading:6262914-Lung Neoplasms,
pubmed-meshheading:6262914-Manganese,
pubmed-meshheading:6262914-Membrane Potentials
|
| pubmed:year |
1981
|
| pubmed:articleTitle |
Calcium spike electrogenesis and other electrical activity in continuously cultured small cell carcinoma of the lung.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|