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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1978-4-17
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pubmed:abstractText |
The cytogenetic effects of Myleran were examined in bone-marrow cells from male mice. To study the dose--response relationship the male mice were injected with 5, 10, 20 or 40 mg of Myleran/kg. Bone-marrow samples were prepared 24 h later. The time response was investigated by examining bone-marrow samples 1, 2, 4 or 10 days after i.p. injection of 40 mg of Myleran. Most of the structural aberrations were of the chromatid type and the dose--response relationship was linear. The chromatid and chromosomal aberrations were maximal at 2 days and decreased sharply after longer intervals of time.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0027-5107
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
56
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
329-33
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:625305-Animals,
pubmed-meshheading:625305-Bone Marrow,
pubmed-meshheading:625305-Busulfan,
pubmed-meshheading:625305-Chromosome Aberrations,
pubmed-meshheading:625305-Chromosomes,
pubmed-meshheading:625305-Dose-Response Relationship, Drug,
pubmed-meshheading:625305-Male,
pubmed-meshheading:625305-Mice,
pubmed-meshheading:625305-Mice, Inbred BALB C,
pubmed-meshheading:625305-Time Factors
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pubmed:year |
1978
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pubmed:articleTitle |
Cytogenetic effects of myleran in vivo on bone-marrow cells from male mice.
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pubmed:publicationType |
Journal Article,
In Vitro
|