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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1976-9-1
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pubmed:abstractText |
Lung function can be reduced not only by a non-selective beta-blocker but also by a selective beta1-receptor blocker. If both types of drug are without intrinsic sympathomimetic activity, the effect of the non-selective drug is more pronounced than that of a beta1-receptor selective drug under basal conditions. The effect of a beta2-receptor stimulating drug on the bronchi is inhibited by a non-selective drug, but much less by a selective beta1-receptor blocker. A selective beta1-receptor blocker can be used in asthmatics when it is combined with optimal anti-asthmatic therapy, while a non-selective drug is contra-indicated in patients with broncho-obstructive diseases. It is necessary to induce bronchodilatation (e.g. with a beta2-stimulator) in order to test whether or not a beta-blocker can be used in broncho-obstructive disease.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0012-6667
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
11 SUPPL 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
171-7
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:6250-Adrenergic beta-Agonists,
pubmed-meshheading:6250-Adrenergic beta-Antagonists,
pubmed-meshheading:6250-Asthma,
pubmed-meshheading:6250-Clinical Trials as Topic,
pubmed-meshheading:6250-Drug Therapy, Combination,
pubmed-meshheading:6250-Forced Expiratory Volume,
pubmed-meshheading:6250-Heart Rate,
pubmed-meshheading:6250-Humans,
pubmed-meshheading:6250-Isoproterenol,
pubmed-meshheading:6250-Lung,
pubmed-meshheading:6250-Lung Diseases, Obstructive
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pubmed:year |
1976
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pubmed:articleTitle |
Use of beta-adrenoreceptor blockers in combination with beta-stimulators in patients with obstructive lung disease.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study
|