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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1980-10-24
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pubmed:abstractText |
Adult mice resistant to infection with 10(6) plaque-forming units of a virulent strain of herpes simplex virus type 1 were treated with 89Sr to abrogate marrow-dependent cell functions. Treated mice were found to be much more susceptible to the herpes simplex virus type 1 infection than untreated mice. The virus persisted in the visceral tissues of 89Sr-treated mice for 3 or more days postinfection but not in those of untreated mice. The virus also spread to the spinal cords of treated but not untreated mice. A marrow-dependent cell appeared to mediate resistance to herpes simplex virus type 1 by controlling the infection early after inoculation and not allowing the infection spread to the central nervous system.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/6249746-109389,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6249746-14207057,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6249746-14467923,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6249746-165599,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6249746-171586,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6249746-192810,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6249746-196023,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6249746-197016,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6249746-217830,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6249746-221611,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6249746-227799,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6249746-300411,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6249746-336380,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6249746-4315460,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6249746-4315461,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6249746-4369740,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6249746-4397663,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6249746-4405320,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6249746-681747,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6249746-781225
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0019-9567
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1028-32
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:6249746-Animals,
pubmed-meshheading:6249746-Antigens, Viral,
pubmed-meshheading:6249746-Bone Marrow,
pubmed-meshheading:6249746-Fluorescent Antibody Technique,
pubmed-meshheading:6249746-Herpes Simplex,
pubmed-meshheading:6249746-Immunity, Innate,
pubmed-meshheading:6249746-Mice,
pubmed-meshheading:6249746-Simplexvirus,
pubmed-meshheading:6249746-Spinal Cord,
pubmed-meshheading:6249746-Strontium Radioisotopes
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pubmed:year |
1980
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pubmed:articleTitle |
Marrow-dependent cells depleted by 89Sr mediate genetic resistance to herpes simplex virus type 1 infection in mice.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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