|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1
|
|
pubmed:dateCreated |
1978-4-17
|
|
pubmed:abstractText |
Vagal activation of gastric acid secretion by modified sham feeding in six patients with duodenal ulcer produced a peak acid response amounting to 52% of the peak acid output after pentagastrin stimulation (PAOpg). Cholinergic reflex stimulation of gastric acid secretion by fundic distension in another six patients with duodenal ulcer produced a peak acid response of 45% of PAOpg. Intravenous infusion of cimetidine in a dose of 100 mg/h markedly inhibited the acid sham feeding response by 90-100% and almost abolished the acid response to fundic distension. The results suggest that gastric acid secretion evoked by physiological vagal activation in man is profoundly inhibited by H2-receptor blocking agents.
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/624502-10620,
http://linkedlifedata.com/resource/pubmed/commentcorrection/624502-1098968,
http://linkedlifedata.com/resource/pubmed/commentcorrection/624502-1322,
http://linkedlifedata.com/resource/pubmed/commentcorrection/624502-13902299,
http://linkedlifedata.com/resource/pubmed/commentcorrection/624502-13902300,
http://linkedlifedata.com/resource/pubmed/commentcorrection/624502-178568,
http://linkedlifedata.com/resource/pubmed/commentcorrection/624502-234769,
http://linkedlifedata.com/resource/pubmed/commentcorrection/624502-239346,
http://linkedlifedata.com/resource/pubmed/commentcorrection/624502-4150859,
http://linkedlifedata.com/resource/pubmed/commentcorrection/624502-4205,
http://linkedlifedata.com/resource/pubmed/commentcorrection/624502-4212027,
http://linkedlifedata.com/resource/pubmed/commentcorrection/624502-4215124,
http://linkedlifedata.com/resource/pubmed/commentcorrection/624502-4401751,
http://linkedlifedata.com/resource/pubmed/commentcorrection/624502-4818397,
http://linkedlifedata.com/resource/pubmed/commentcorrection/624502-4854753,
http://linkedlifedata.com/resource/pubmed/commentcorrection/624502-5342,
http://linkedlifedata.com/resource/pubmed/commentcorrection/624502-6359,
http://linkedlifedata.com/resource/pubmed/commentcorrection/624502-856669,
http://linkedlifedata.com/resource/pubmed/commentcorrection/624502-863291,
http://linkedlifedata.com/resource/pubmed/commentcorrection/624502-892340,
http://linkedlifedata.com/resource/pubmed/commentcorrection/624502-981959,
http://linkedlifedata.com/resource/pubmed/commentcorrection/624502-9952
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jan
|
|
pubmed:issn |
0017-5749
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
19
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
27-31
|
|
pubmed:dateRevised |
2009-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:624502-Adult,
pubmed-meshheading:624502-Cimetidine,
pubmed-meshheading:624502-Duodenal Ulcer,
pubmed-meshheading:624502-Gastric Juice,
pubmed-meshheading:624502-Guanidines,
pubmed-meshheading:624502-Humans,
pubmed-meshheading:624502-Male,
pubmed-meshheading:624502-Middle Aged,
pubmed-meshheading:624502-Secretory Rate,
pubmed-meshheading:624502-Stomach,
pubmed-meshheading:624502-Vagus Nerve
|
|
pubmed:year |
1978
|
|
pubmed:articleTitle |
Inhibitory effect of cimetidine on gastric acid secretion vagally activated by physiological means in duodenal ulcer patients.
|
|
pubmed:publicationType |
Journal Article
|
