Linked Life Data

6236979

Source:http://linkedlifedata.com/resource/pubmed/id/6236979

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1984-11-9
pubmed:abstractText
Immunocytochemical techniques have been applied to cells infected with human adenovirus type 5 in order to study the distribution of antigens related to the virus-encoded Mr = 72000 (72K) DNA-binding protein. In embedded cells 72K antigen was found to be associated with 'clear' fibrillar inclusions, in which viral DNA replication is known to take place. "Dense" fibrillar inclusions, which are thought to contain previously replicated viral DNA, do not contain detectable levels of 72K antigen, suggesting that the conversion of clear inclusions to dense inclusions is accompanied by loss of the 72K protein. In cells examined by the spreading technique of Miller, 72K antigen is associated with the 10 nm "thick filaments" previously described by several laboratories, consistent with the established role of the 72K protein in viral replication complexes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0171-9335
pubmed:author
pubmed:issnType
Print
pubmed:volume
34
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
313-22
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Identification of intranuclear structures containing the 72K DNA-binding protein of human adenovirus type 5.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't