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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1984-1-7
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pubmed:abstractText |
The effect of two years of periodic transfusions at 2--4 month intervals of mixed leukocytes in a patient with Type I mucopolysaccharidosis is described. There was an increase of urinary chondroitin sulfate B after the first transfusion followed by a progressive decrease to 35% of the initial daily excretion. Chondroitin sulfate AC, which was almost absent prior to the transfusions, was excreted in significant amounts after the 4th transfusion. There was a decrease of hepatosplenomegaly, kyphosis and gibbus and no changes in the other signs of the disease. Regarding stature, mental development and social behavior, the patient is developing thus far as a normal child. The early diagnosis of the disease and the immediate transfusions undoubtedly have been contributing factors to the restoration and/or maintenance of the child in an almost normal condition.
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0100-879X
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
16
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
29-33
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6227354-Blood Transfusion,
pubmed-meshheading:6227354-Chondroitin Sulfates,
pubmed-meshheading:6227354-Female,
pubmed-meshheading:6227354-Glycosaminoglycans,
pubmed-meshheading:6227354-Humans,
pubmed-meshheading:6227354-Infant,
pubmed-meshheading:6227354-Leukocyte Transfusion,
pubmed-meshheading:6227354-Mucopolysaccharidosis I
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pubmed:year |
1983
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pubmed:articleTitle |
Clinical and biochemical changes in a child with type I mucopolysaccharidosis during long-term transfusion of leukocytes.
|
pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
|