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rdf:type |
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lifeskim:mentions |
umls-concept:C0003873,
umls-concept:C0004083,
umls-concept:C0009511,
umls-concept:C0026473,
umls-concept:C0031307,
umls-concept:C0031308,
umls-concept:C0032659,
umls-concept:C0175630,
umls-concept:C0205245,
umls-concept:C0205370,
umls-concept:C0243067,
umls-concept:C0332120,
umls-concept:C0700364,
umls-concept:C1513475
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pubmed:issue |
5
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pubmed:dateCreated |
1983-11-23
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pubmed:abstractText |
We have previously described a selective defect of monocyte C3b receptor-mediated phagocytosis in patients with rheumatoid cutaneous vasculitis. We have studied a further 15 rheumatoid arthritis patients with other associated diseases and complications and have identified 4 further patients with a similar defect. Serological and cytochemical studies suggest that the defect in phagocytosis is due to the appearance of increased numbers of large nonspecific esterase-negative mononuclear phagocytes with defective C3b receptor phagocytic function rather than to receptor blockade by immune complexes.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/6226245-13631241,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6226245-4179068,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6226245-4183354,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6226245-479604,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6226245-5014610,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6226245-5549896,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6226245-6112603,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6226245-6788211,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6226245-7360040,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6226245-944196,
http://linkedlifedata.com/resource/pubmed/commentcorrection/6226245-974266
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0003-4967
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
42
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
487-93
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:6226245-Adult,
pubmed-meshheading:6226245-Aged,
pubmed-meshheading:6226245-Arthritis, Rheumatoid,
pubmed-meshheading:6226245-Carboxylesterase,
pubmed-meshheading:6226245-Carboxylic Ester Hydrolases,
pubmed-meshheading:6226245-Complement Inactivator Proteins,
pubmed-meshheading:6226245-Female,
pubmed-meshheading:6226245-Humans,
pubmed-meshheading:6226245-Kinetics,
pubmed-meshheading:6226245-Male,
pubmed-meshheading:6226245-Middle Aged,
pubmed-meshheading:6226245-Monocytes,
pubmed-meshheading:6226245-Phagocytosis,
pubmed-meshheading:6226245-Receptors, Complement,
pubmed-meshheading:6226245-Receptors, Complement 3b,
pubmed-meshheading:6226245-Receptors, Fc,
pubmed-meshheading:6226245-Vasculitis
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pubmed:year |
1983
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pubmed:articleTitle |
Functional defects of monocyte C3b receptor-mediated phagocytosis in rheumatoid arthritis (RA): evidence for an association with the appearance of a circulating population of non-specific esterase-negative mononuclear phagocytes.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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