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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1984-12-5
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pubmed:abstractText |
An immunoradiometric assay using a monoclonal antibody detects an antigenic determinant (CA125) that is present in more than 80% of epithelial ovarian cancers. CA125 levels are elevated in the sera of 16% of women in the first trimester of pregnancy and is found in very high concentration in amniotic fluid. In 988 nonpregnant patients with benign gynecologic disorders, CA125 was greater than 65 U/mL in 1% on a single determination and in 0.5% with two determinations. Given the low rate of positivity in benign gynecologic disease, the CA125 assay may deserve further evaluation for the early detection of ovarian carcinoma.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
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pubmed:issn |
0029-7844
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
703-7
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pubmed:dateRevised |
2009-10-26
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pubmed:meshHeading |
pubmed-meshheading:6208522-Adult,
pubmed-meshheading:6208522-Aged,
pubmed-meshheading:6208522-Amniotic Fluid,
pubmed-meshheading:6208522-Antibodies, Monoclonal,
pubmed-meshheading:6208522-Antigens, Neoplasm,
pubmed-meshheading:6208522-Antigens, Tumor-Associated, Carbohydrate,
pubmed-meshheading:6208522-Epitopes,
pubmed-meshheading:6208522-Female,
pubmed-meshheading:6208522-Genital Diseases, Female,
pubmed-meshheading:6208522-Humans,
pubmed-meshheading:6208522-Middle Aged,
pubmed-meshheading:6208522-Ovarian Neoplasms,
pubmed-meshheading:6208522-Pregnancy,
pubmed-meshheading:6208522-Radioimmunoassay
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pubmed:year |
1984
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pubmed:articleTitle |
CA125 antigen levels in obstetric and gynecologic patients.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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