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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1984-9-24
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pubmed:abstractText |
Vasoactive intestinal polypeptide (VIP)- and substance P-containing nerve fibers were observed in the cerebral blood vessels using an immunohistochemical technique. VIP-containing nerve fibers distributed in a spiral pattern, similar to that of muscle cells. Under electron microscopic observation, VIP-immunoreactive terminals lay close to a muscle cell in the inner layer of the adventitia. In contrast, substance P-containing nerve fibers showed a meshwork pattern in the outer layer of the adventitia. Using both acetylcholinesterase (AChE) staining and VIP immunohistochemistry, AChE-positive and VIP-immunoreactive nerve fibers revealed almost the same distribution in the same specimen. The present data suggest that VIP-containing nerve fibers may play a role in the smooth muscle control of the blood vessels, whereas substance P-containing nerve fibers may not take part in muscle control.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0271-678X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
4
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
407-14
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6206080-Animals,
pubmed-meshheading:6206080-Blood Vessels,
pubmed-meshheading:6206080-Cerebrovascular Circulation,
pubmed-meshheading:6206080-Guinea Pigs,
pubmed-meshheading:6206080-Histocytochemistry,
pubmed-meshheading:6206080-Immunochemistry,
pubmed-meshheading:6206080-Microscopy, Electron,
pubmed-meshheading:6206080-Nerve Fibers,
pubmed-meshheading:6206080-Parasympathetic Nervous System,
pubmed-meshheading:6206080-Substance P,
pubmed-meshheading:6206080-Sympathetic Nervous System,
pubmed-meshheading:6206080-Vasoactive Intestinal Peptide
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pubmed:year |
1984
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pubmed:articleTitle |
A light and electron microscopic immunohistochemical study of vasoactive intestinal polypeptide- and substance P-containing nerve fibers along the cerebral blood vessels: comparison with aminergic and cholinergic nerve fibers.
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pubmed:publicationType |
Journal Article,
Comparative Study
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