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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1984-2-24
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pubmed:abstractText |
A reversed-phase liquid chromatographic method with amperometric detection has been developed for the simultaneous determination of the noradrenaline metabolite, vanilmandelic acid, the dopamine metabolite, homovanillic acid, and the serotonin metabolite, 5-hydroxyindole acetic acid, in human urine. After purification by an extraction procedure, the metabolites were rapidly separated under isocratic conditions. Detection and quantification were performed with an electrochemical detector using a carbon paste electrode. The present method is sensitive, selective and, achieves a high degree of precision by the use of isovanilmandelic acid as an internal standard. This provides a suitable tool for clinical and research applications.
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0160-5402
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
10
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
193-8
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6197590-Chromatography, High Pressure Liquid,
pubmed-meshheading:6197590-Electrochemistry,
pubmed-meshheading:6197590-Homovanillic Acid,
pubmed-meshheading:6197590-Humans,
pubmed-meshheading:6197590-Hydroxyindoleacetic Acid,
pubmed-meshheading:6197590-Phenylacetates,
pubmed-meshheading:6197590-Vanilmandelic Acid
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pubmed:year |
1983
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pubmed:articleTitle |
Assay of urinary vanilmandelic, homovanillic, and 5-hydroxyindole acetic acids by liquid chromatography with electrochemical detection.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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