Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1983-10-8
pubmed:abstractText
Investigations carried out by the authors have demonstrated that a new specially synthesized nonionic detergent, MECK, can be successfully used for obtaining pure influenza virus surface antigens in preparative amounts. Hemagglutinin and neuraminidase isolated by means of MECK retain their structure and biological activity. Special attention has been devoted to the study of the immunological characteristics of the preparations thus obtained. The high immunogenicity of solubilized hemagglutinin and the complete retention of its antigenic activity have been confirmed. The simplicity of the method for the isolation of influenza virus surface antigens and their purification from internal viral proteins and the detergent make it possible to recommend the above method for the preparative isolation of external antigens.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0372-9311
pubmed:author
pubmed:issnType
Print
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
81-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
[Isolation of purified glycoproteins of influenza virus and analysis of their antigenic and immunogenic activity].
pubmed:publicationType
Journal Article, English Abstract