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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
1983-10-21
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pubmed:abstractText |
Small transformed cell lymphoma (STC) is the least common follicular center cell neoplasm in the Lukes-Collins classification system. If the cells are homogenous in size and shape, Burkitt's lymphoma (STC-BL) is diagnosed; otherwise STC lymphoma of the non-Burkitt's type (STC-nBL) is present. The authors have reviewed their experience with 17 cases of STC-nBL. This neoplasm affects all ages, both sexes equally, and most commonly is Stage IV based either on a visceral abdominal mass or bone marrow involvement. Surface immunoglobulin analysis revealed IgM in all cases tested. In spite of aggressive treatment protocols, there were only 5 of 17 (29%) clinical complete responses. Four of these five have continuous remission from 8 to 23 months after diagnosis; all four of these patients were treated with regimens containing high-dose cyclophosphamide. Future analyses including viral studies, chromosomal analyses, and uniform treatment protocols will help determine whether STC-nBL and Burkitt's lymphoma are truly distinct entities.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0008-543X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1196-201
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6192896-Adolescent,
pubmed-meshheading:6192896-Adult,
pubmed-meshheading:6192896-Aged,
pubmed-meshheading:6192896-Bone Marrow,
pubmed-meshheading:6192896-Child,
pubmed-meshheading:6192896-Child, Preschool,
pubmed-meshheading:6192896-Female,
pubmed-meshheading:6192896-Hematocrit,
pubmed-meshheading:6192896-Humans,
pubmed-meshheading:6192896-L-Lactate Dehydrogenase,
pubmed-meshheading:6192896-Lymphoma,
pubmed-meshheading:6192896-Male,
pubmed-meshheading:6192896-Middle Aged,
pubmed-meshheading:6192896-Neoplasm Staging,
pubmed-meshheading:6192896-Staining and Labeling
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pubmed:year |
1983
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pubmed:articleTitle |
Malignant lymphoma of follicular center cell origin in humans. IV. Small transformed (noncleaved) cell lymphoma of the non-Burkitt's type.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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