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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1983-9-20
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pubmed:abstractText |
1. Cytochrome P-448 from beta-naphthoflavone treated rainbow trout (Salmo gairdnerii) liver was purified and compared to purified P-448 from beta-naphthoflavone treated rats (Rattus rattus) and purified P-450 from phenobarbital induced rats. 2. The two P-448 forms had similar spectral properties, substrate specificity, sensitivity to inhibitors and regioselectivity in the metabolism of benzo(a)pyrene and testosterone. 3. Rat and trout P-448 differed in apparent monomeric mol. wt (Mr) by at least 2000 daltons, and did not share identical antigenic determinants. Both rat and trout P-448 were shown to be quite different from rat P-450 using all of the above criteria for distinguishing multiple forms.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Benzo(a)pyrene,
http://linkedlifedata.com/resource/pubmed/chemical/Benzoflavones,
http://linkedlifedata.com/resource/pubmed/chemical/Benzopyrene Hydroxylase,
http://linkedlifedata.com/resource/pubmed/chemical/Benzopyrenes,
http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 Enzyme System,
http://linkedlifedata.com/resource/pubmed/chemical/Cytochromes,
http://linkedlifedata.com/resource/pubmed/chemical/Epitopes,
http://linkedlifedata.com/resource/pubmed/chemical/Flavonoids,
http://linkedlifedata.com/resource/pubmed/chemical/Phenobarbital,
http://linkedlifedata.com/resource/pubmed/chemical/Testosterone,
http://linkedlifedata.com/resource/pubmed/chemical/beta-Naphthoflavone,
http://linkedlifedata.com/resource/pubmed/chemical/cytochrome P-448
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pubmed:status |
MEDLINE
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pubmed:issn |
0742-8413
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
75
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
25-32
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:6191918-Animals,
pubmed-meshheading:6191918-Benzo(a)pyrene,
pubmed-meshheading:6191918-Benzoflavones,
pubmed-meshheading:6191918-Benzopyrene Hydroxylase,
pubmed-meshheading:6191918-Benzopyrenes,
pubmed-meshheading:6191918-Cytochrome P-450 Enzyme System,
pubmed-meshheading:6191918-Cytochromes,
pubmed-meshheading:6191918-Epitopes,
pubmed-meshheading:6191918-Flavonoids,
pubmed-meshheading:6191918-Microsomes, Liver,
pubmed-meshheading:6191918-Phenobarbital,
pubmed-meshheading:6191918-Rats,
pubmed-meshheading:6191918-Salmonidae,
pubmed-meshheading:6191918-Species Specificity,
pubmed-meshheading:6191918-Spectrophotometry,
pubmed-meshheading:6191918-Substrate Specificity,
pubmed-meshheading:6191918-Testosterone,
pubmed-meshheading:6191918-Trout,
pubmed-meshheading:6191918-beta-Naphthoflavone
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pubmed:year |
1983
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pubmed:articleTitle |
Comparative properties of purified cytochrome P-448 from beta-naphthoflavone treated rats and rainbow trout.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.
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