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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1983-8-26
|
| pubmed:abstractText |
Fetal suppressor cells are potentially important for maintenance of pregnancy and for the immune regulation of the identification of self. We have identified and partially characterized a population of murine fetal liver cells which are active suppressors of a variety of immune responses, including mixed lymphocyte responses (MLR), responses to mitogens, and plaque-forming cell responses to heterologous erythrocytes. The suppression is non-H-2-restricted and can act via a factor. The cell is preactivated in fetal liver and may represent a T-cell precursor. The suppression of MLR is maximal (approximately 100%) if cells are added within the first 48 h of culture initiation. The characteristics of this suppressor cell are compared to other known MLR and perinatal suppressor systems.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0271-7352
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
3
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
132-6
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:6191583-Animals,
pubmed-meshheading:6191583-Antibody-Producing Cells,
pubmed-meshheading:6191583-Cell Adhesion,
pubmed-meshheading:6191583-Cell Separation,
pubmed-meshheading:6191583-Epitopes,
pubmed-meshheading:6191583-Female,
pubmed-meshheading:6191583-Fetus,
pubmed-meshheading:6191583-H-2 Antigens,
pubmed-meshheading:6191583-Hemolytic Plaque Technique,
pubmed-meshheading:6191583-Kinetics,
pubmed-meshheading:6191583-Liver,
pubmed-meshheading:6191583-Lymphocyte Activation,
pubmed-meshheading:6191583-Lymphocyte Culture Test, Mixed,
pubmed-meshheading:6191583-Mice,
pubmed-meshheading:6191583-Mice, Inbred BALB C,
pubmed-meshheading:6191583-Mice, Inbred C57BL,
pubmed-meshheading:6191583-Pregnancy,
pubmed-meshheading:6191583-T-Lymphocytes, Regulatory
|
| pubmed:articleTitle |
The identification of suppressor cells in the murine fetal liver.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|