Linked Life Data

6179136

Source:http://linkedlifedata.com/resource/pubmed/id/6179136

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1982-9-24
pubmed:abstractText
The elimination of high molecular weight hydroxyethyl starch (HMW-HES) was determined in dogs. . Eight dogs were divided into two groups; one of which was bled 25 ml/kg. Both groups were given 25 ml/kg of 6% HMW-HES solution over a 30 min period. There was no significant difference in plasma concentration vs time profiles between the two groups. The biological half-life estimated between days 7-28, averaged 7.5 and 8.4 days in control and bled dogs, respectively. The renal clearance of HMW-HES diminished considerably in both groups during the 7 day period. Despite large interanimal variations in renal clearance, there was not a significant difference between groups.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0034-5164
pubmed:author
pubmed:issnType
Print
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
199-204
pubmed:dateRevised
2009-11-3
pubmed:meshHeading
pubmed:year
1982
pubmed:articleTitle
Pharmacokinetics of high molecular weight hydroxyethyl starch in dogs.
pubmed:publicationType
Journal Article