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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1982-3-13
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pubmed:abstractText |
A 7-year-old girl suffering from chronic diarrhoea due to sucrase deficiency was referred because of poor hair growth. Her scalp hair had a poor, colourless appearance and was much thinned in the occipital region. Her skin was dry, but otherwise normal. P-zinc was low (7.9 mumol/l), whereas P-albumin was normal. Oral zinc therapy, 40 mg daily, had a marked beneficial effect on her scalp hair, eyebrows and eyelashes, which became thicker and pigmented. Beau lines appeared on thumb-nails and 4th left finger-nail. A rise in P-zinc and S-alkaline phosphatase levels was observed during the zinc supplementation. Microscopic examination of her poor scalp hair, using polarized light, revealed well-defined abnormalities of the hair shafts, as reported by others in a case of acrodermatitis enteropathica: 1) a marked individual variation in diameter, 2) narrowing often associated with waving or sharp bending and broken ends, 3) striation with a tendency to trichonodosis. Such changes were absent in the pigmented hair appearing after the start of zinc therapy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Alkaline Phosphatase,
http://linkedlifedata.com/resource/pubmed/chemical/Sucrose,
http://linkedlifedata.com/resource/pubmed/chemical/Sulfates,
http://linkedlifedata.com/resource/pubmed/chemical/Zinc,
http://linkedlifedata.com/resource/pubmed/chemical/Zinc Sulfate
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pubmed:status |
MEDLINE
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pubmed:issn |
0001-5555
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
444-7
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:6172938-Alkaline Phosphatase,
pubmed-meshheading:6172938-Carbohydrate Metabolism, Inborn Errors,
pubmed-meshheading:6172938-Child,
pubmed-meshheading:6172938-Diarrhea,
pubmed-meshheading:6172938-Female,
pubmed-meshheading:6172938-Hair Diseases,
pubmed-meshheading:6172938-Humans,
pubmed-meshheading:6172938-Sucrose,
pubmed-meshheading:6172938-Sulfates,
pubmed-meshheading:6172938-Zinc,
pubmed-meshheading:6172938-Zinc Sulfate
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pubmed:year |
1981
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pubmed:articleTitle |
Hair changes due to zinc deficiency in a case of sucrose malabsorption.
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pubmed:publicationType |
Journal Article,
Case Reports
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