Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1980-11-20
pubmed:abstractText
Recent studies of central nervous system effects on pain and on its efferent modulation have created new theories and have led to direct clinical applications that may in time eclipse more classical interventions. In this review electrical stimulation analgesia is presented as a paradigm of how basic science work has been applied clinically to produce some of the most exciting advances in recent years in the treatment of chronic pain. Opiate receptors and analgesia are presented in relationship to the descending inhibitory systems used in electroanalgesia. Neuromodulators and neurotransmitters important in pain modulation through complex inhibitory and excitatory pathways are discussed, with the roles of B-endorphin, enkephalin, serotonin, and other important biogenic amines being stressed. The neuropharmacology of pain as it is currently understood clinically suggests that psychotropic interventions may be quite useful in treating difficult pain problems.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0148-396X
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
584-90
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Pain and its modulation. Part 2. efferent mechanisms.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Review