Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7990
pubmed:dateCreated
1976-12-3
pubmed:abstractText
An indirect immunofluorescence technique and an indirect immunoperoxidase technique were used on cryostat sections of human group-O submaxillary salivary gland and rat stomach. Circulating antibodies reacting with mucus antigen(s) were found in sera from 52-7% of patients with active pulmonary tuberculosis and in 21-8% of patients with chronic obstructive lung disease. Among hospital patients with other diseases and healthy controls, mucus antibodies were found in 7-2 and 5.4% respectively. The mucus antibodies were not absorbed by an excess of red blood-cells derived from group AD+ healthy subjects or from the rat donor of the stomach, while the fluorescence and the immunoperoxidase reactions were almost completely abolished after the absorption of positive sera with human dried bronchial secretion. It is postulated that mucus antibody may be a new and important serological marker of disorders accompanied by mucus accumulation in the lung and possibly other organs and/or by severe changes of the anatomical structures which act as a barrier to the reabsorption of abnormal amounts of mucus.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0140-6736
pubmed:author
pubmed:issnType
Print
pubmed:day
16
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
821-4
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Mucus antibodies in pulmonary tuberculosis and chronic obstructive lung disease.
pubmed:publicationType
Journal Article