Linked Life Data

6149484

Source:http://linkedlifedata.com/resource/pubmed/id/6149484

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1984-12-18
pubmed:abstractText
Far-field potentials (FFPs) were studied in monkeys to determine the utility of such responses in evaluating acute and chronic spinal cord injury. Monkeys (Macaca fascicularis) were anesthetized with 70% N2O 30% O2, immobilized with pancuronium bromide, and maintained on a respirator. Spinal cord transections were made at level T3-T4 and included bilateral dorsal columns or anterolateral columns, right or left hemisection, or central cord lesions. Percutaneous stimulation of both posterior tibial nerves was performed at a frequency of 3 Hz using 3-4 mA for 0.3 msec duration. Potentials were recorded from chronically implanted epidural electrodes (right ear reference) through a 300-3,000 Hz band pass filter. Each far-field potential represents the average of 256 individual responses recorded for a duration of 25 msec before and after cord lesion for up to 8 weeks. Seven reproducible components in the far-field potential could be identified. Following dorsal column transection all components were reduced in amplitude. After anterolateral column transection only latencies were altered. Right or left hemisections caused both attenuation of component amplitudes and latency alteration. Central cord lesions resulted in no detectable amplitude or latency disturbances. Control records likewise showed no changes. No major alterations, following day 1 posttransection, were observed, attesting to the relative stability of far-field potentials over long periods of time. Far-field potentials therefore may be useful in monitoring spinal cord injury.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0161-6412
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
13-27
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1983
pubmed:articleTitle
Far-field potentials as a method of monitoring acute and chronic spinal cord injury.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.