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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1984-8-13
|
| pubmed:abstractText |
A new family of beta-blocking drugs is described. The originality of the new molecules lies in their functionalized hydrophobic folded structure, the basic part of which contains a benzocyclobutene ring. Excellent beta 2-blocker selectivity has been obtained with some of these compounds. Interestingly, this selectivity was not modified toward beta 1-blocker activity by introduction of the usual beta 1 inducer groups.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0022-2623
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
27
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
792-9
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:6145801-Adrenergic beta-Antagonists,
pubmed-meshheading:6145801-Animals,
pubmed-meshheading:6145801-Blood Pressure,
pubmed-meshheading:6145801-Guinea Pigs,
pubmed-meshheading:6145801-Heart Rate,
pubmed-meshheading:6145801-Isoproterenol,
pubmed-meshheading:6145801-Muscle Relaxation,
pubmed-meshheading:6145801-Propanolamines
|
| pubmed:year |
1984
|
| pubmed:articleTitle |
Synthesis of a novel series of (aryloxy)propanolamines: new selective beta 2-blocking agents.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|