Linked Life Data

6141883

Source:http://linkedlifedata.com/resource/pubmed/id/6141883

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1984-3-29
pubmed:abstractText
Daily oral exposure of rats to 30 mg/kg of Aroclor 1254 for 1 month caused deleterious effects on the reproductive process, which were reflected in a decrease in the reproductive potential. The following disturbances were observed: prolongation of the estrous cycle; decrease in sexual receptivity; delay in timing of copulation; vaginal bleeding during gestation; decrease in litter size and delay in the time of parturition. The offspring, whether exposed to PCBs either prenatally and/or postnatally, showed a slower rate of body weight gain than controls. This was accompanied by high mortality until weaning of treated pups. Vaginal opening in the PCB-treated (as young) females occurred precociously, while other reproductive parameters were not affected at adulthood. Discontinuance of PCB treatment reversed the above symptoms.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0742-8413
pubmed:author
pubmed:issnType
Print
pubmed:volume
77
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
65-70
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
The effect of Aroclor 1254 (PCB) on the physiology of reproduction in the female rat--I.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't