| pubmed-article:6132635 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:6132635 | lifeskim:mentions | umls-concept:C0019588 | lld:lifeskim |
| pubmed-article:6132635 | lifeskim:mentions | umls-concept:C0681916 | lld:lifeskim |
| pubmed-article:6132635 | lifeskim:mentions | umls-concept:C0750572 | lld:lifeskim |
| pubmed-article:6132635 | lifeskim:mentions | umls-concept:C1160577 | lld:lifeskim |
| pubmed-article:6132635 | lifeskim:mentions | umls-concept:C0243076 | lld:lifeskim |
| pubmed-article:6132635 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
| pubmed-article:6132635 | lifeskim:mentions | umls-concept:C0680844 | lld:lifeskim |
| pubmed-article:6132635 | lifeskim:mentions | umls-concept:C1510438 | lld:lifeskim |
| pubmed-article:6132635 | lifeskim:mentions | umls-concept:C0042295 | lld:lifeskim |
| pubmed-article:6132635 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:6132635 | pubmed:dateCreated | 1983-6-10 | lld:pubmed |
| pubmed-article:6132635 | pubmed:abstractText | 1 Histamine H2-receptor antagonism by burimamide, metiamide and cimetidine was analysed under apparent equilibrium conditions in the lumen-perfused isolated stomach preparation of the mouse. 2 The behaviour of these compounds was not incompatible with simple competitive antagonism but the estimated pKB values (-log KB) were all significantly lower, by about 1 log unit, than reference values reported for guinea-pig atrium or rat uterus. 3 There seems no need to propose that the parietal cell receptors are somehow different from the others; metiamide continually appears in the gastric juice so that a steady-state but not equilibrium can presumably be reached with respect to the bath concentration and this could keep the antagonist concentration artificially low in the region of the receptors. | lld:pubmed |
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| pubmed-article:6132635 | pubmed:language | eng | lld:pubmed |
| pubmed-article:6132635 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:6132635 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:6132635 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:6132635 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:6132635 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:6132635 | pubmed:issn | 0007-1188 | lld:pubmed |
| pubmed-article:6132635 | pubmed:author | pubmed-author:BlackJ WJW | lld:pubmed |
| pubmed-article:6132635 | pubmed:author | pubmed-author:StoneMM | lld:pubmed |
| pubmed-article:6132635 | pubmed:author | pubmed-author:AngusJ AJA | lld:pubmed |
| pubmed-article:6132635 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:6132635 | pubmed:volume | 68 | lld:pubmed |
| pubmed-article:6132635 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:6132635 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:6132635 | pubmed:pagination | 413-23 | lld:pubmed |
| pubmed-article:6132635 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:6132635 | pubmed:meshHeading | pubmed-meshheading:6132635-... | lld:pubmed |
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| pubmed-article:6132635 | pubmed:meshHeading | pubmed-meshheading:6132635-... | lld:pubmed |
| pubmed-article:6132635 | pubmed:year | 1980 | lld:pubmed |
| pubmed-article:6132635 | pubmed:articleTitle | Estimation of pKB values for histamine H2-receptor antagonists using an in vitro acid secretion assay. | lld:pubmed |
| pubmed-article:6132635 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:6132635 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:6132635 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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