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pubmed:abstractText |
We examined 10 patients with an exercise-induced asthma. Physical exercise was carried out under placebo, 40 mg propranolol, 5 mg pindolol and 50 mg metoprolol, respectively, before and after alpha blockade. After exercise, we noted a distinct increase of airway resistance in all cases, the increase of which, however, was lower after a preceding alpha blockade. Under propranolol, the increase of the airway resistance and of norepinephrine, as compared with pindolol, metoprolol, and placebo, was most intensive.
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