Linked Life Data

6127156

Source:http://linkedlifedata.com/resource/pubmed/id/6127156

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1982-12-18
pubmed:abstractText
Various antipsychotic and antidepressant drugs have been tested for their effects on the binding of [3H] phorbol-dibutyrate (PDBu) to its specific receptor. Chlorpromazine and related antipsychotic tricyclic compounds competitively inhibit the interaction between tumor-promoting phorbol esters and their specific receptors. The relative potency of drugs in competing for [3H]PDBU to receptors is fluphenzine greater than flupenthioxal greater than 2-chloroimipramine greater than chlorpromazine greater than imipramine. The significance of these findings is discussed with special reference to the potential tumor-promoting activity of these drugs.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0304-3835
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
171-7
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:articleTitle
Chlorpromazine and related antipsychotic tricyclic compounds competitively inhibit the interaction between tumor-promoting phorbol esters and their specific receptors.
pubmed:publicationType
Journal Article