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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1982-10-29
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pubmed:abstractText |
A human cell membrane antigen that is highly T-cell specific among a number of leukocyte cell lines was isolated from cells of a human T-cell leukemia cell line, SKW-3. In addition to the high specificity to T-cell-type cell lines, the isolated antigen showed the following characteristics: (1) It is an acidic glycoprotein of approximately 30 000 daltons that has a charge heterogeneity and probably a disulfide bond(s); (2) Its antigenicity is stable when treated with heat, acid, and various protein denaturants; (3) It is widely distributed in lymphoid and nonlymphoid tissues but is most predominant in brain. These features are similar, if not identical, to those reported for the Thy-1 antigen of mouse or rat and have raised the possibility that this cell membrane antigen may correspond to human "lymphocyte" Thy-1 antigen, the counterpart of human "brain" Thy-1 antigen.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0093-7711
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
551-63
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:6125472-Antigens, Neoplasm,
pubmed-meshheading:6125472-Antigens, Surface,
pubmed-meshheading:6125472-Antigens, Thy-1,
pubmed-meshheading:6125472-Brain,
pubmed-meshheading:6125472-Cell Line,
pubmed-meshheading:6125472-Glycoproteins,
pubmed-meshheading:6125472-Humans,
pubmed-meshheading:6125472-Leukemia, Lymphoid,
pubmed-meshheading:6125472-Male,
pubmed-meshheading:6125472-Molecular Weight,
pubmed-meshheading:6125472-Organ Specificity,
pubmed-meshheading:6125472-T-Lymphocytes,
pubmed-meshheading:6125472-Testis
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pubmed:year |
1982
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pubmed:articleTitle |
A human thy-1-like antigen expressed on cultured leukemic T-cells.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.
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