Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1982-10-21
pubmed:abstractText
Pharmacology is the study of the properties of a drug with respect to its interaction with the host, toxicology, and with the disease, therapeutics. Since both the toxicology and therapeutic activity of L-asparaginase are presented by others at this symposium, I will give only a brief overview of the pharmacology of L-asparaginase with particular reference to how it differs from other chemotherapeutic agents. Primarily, I would like to discuss how it may be possible to modify some of the pharmacological constraints on the therapeutic responses to L-asparaginase by combining the enzyme with inhibitors of asparagine synthetase and by using polymer-modified forms of the enzyme.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0361-5960
pubmed:author
pubmed:issnType
Print
pubmed:volume
65 Suppl 4
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
47-55
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1981
pubmed:articleTitle
Pharmacology of L-asparaginase and the effects of host and enzyme modification.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S.