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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1982-5-21
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pubmed:abstractText |
A 25-year-old woman with Gilles de la Tourette's disease was successfully treated with clonidine (an inhibitor of noradrenaline release). However, the drug was stopped because of side effects. Thioproperazine, a phenothiazine derivative which blocks subcortical dopaminergic receptors, suppressed Gilles de la Tourette's symptoms totally. The patient has tolerated the drug well for over a year since its introduction. The pharmacomanometric investigation performed in this patient showed hyperactivity of her noradrenergic system.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0006-3223
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
103-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6120723-Adult,
pubmed-meshheading:6120723-Clonidine,
pubmed-meshheading:6120723-Female,
pubmed-meshheading:6120723-Gastrointestinal Motility,
pubmed-meshheading:6120723-Humans,
pubmed-meshheading:6120723-Phenothiazines,
pubmed-meshheading:6120723-Receptors, Adrenergic,
pubmed-meshheading:6120723-Tourette Syndrome
|
pubmed:year |
1982
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pubmed:articleTitle |
On the use of clonidine and thioproperazine in a woman with Gilles de la Tourette's disease.
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pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
|