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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1187
|
pubmed:dateCreated |
1981-8-20
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pubmed:abstractText |
Transient changes in free intracellular Ca2+ concentration were monitored in the presynaptic terminal of the giant synapse of the squid, by means of the Ca2+-sensitive dye arsenazo III. Calibration experiments showed a linear relation between the amount of Ca2+ injected by iontophoresis into the terminal, and the peak size of the arsenazo light absorbance record. A light signal could be detected on tetanic stimulation of the presynaptic axon bathed in sea water containing 45 mM Ca2+. During a 1 s tetanus the light signal rose approximately linearly, even though transmitter release declined rapidly and the light signal subsequently declined with a half-time of 2-6 s. The Ca2+ transient elicited by single nerve impulses was recorded by signal averaging, and showed a time course very much slower than the duration of transmitter release.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
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pubmed:issn |
0080-4649
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
22
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pubmed:volume |
212
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
197-211
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pubmed:dateRevised |
2007-4-30
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pubmed:meshHeading |
pubmed-meshheading:6113595-Animals,
pubmed-meshheading:6113595-Arsenazo III,
pubmed-meshheading:6113595-Axons,
pubmed-meshheading:6113595-Calcium,
pubmed-meshheading:6113595-Decapodiformes,
pubmed-meshheading:6113595-Electric Conductivity,
pubmed-meshheading:6113595-Electric Stimulation,
pubmed-meshheading:6113595-Light,
pubmed-meshheading:6113595-Synapses
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pubmed:year |
1981
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pubmed:articleTitle |
Calcium transients recorded with arsenazo III in the presynaptic terminal of the squid giant synapse.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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