Linked Life Data

6106429

Source:http://linkedlifedata.com/resource/pubmed/id/6106429

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1980-11-25
pubmed:abstractText
The aging of the cells depends on their mitotic activity, which is particularly evident in multicellular organisms. By way of histoautoradiography we studied the cell kinetics on a total of 244 Wistar rats aged 6 days, 6 weeks, 6, 12, 23 and 28 months respectively, with these studies being centred on the mucosa of the small intestine since this mucosa is one of those tissues with the highest cell metabolism. We succeeded in demonstrating that the regeneration rate of cells per hour in the crypts of the small intestine and the migration speed of the enterocytes differ in young and old individuals and that the intermitotic cells have age-dependent properties as well. In addition, we could prove that intermitotic cells too have a non-growth fraction which, at an advanced age, decreases only a little, although significantly in terms of statistics. For the easily vulnerable crypt epithelium it is a reserve capacity and can be included in the proliferating pool, if necessary.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0300-5704
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
225-32
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
[The aging of intermitotic cells (author's transl)].
pubmed:publicationType
Journal Article, English Abstract