Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8193
pubmed:dateCreated
1980-10-27
pubmed:abstractText
In an outbreak of group A streptococcal pharyngitis in a semi-closed community, 42 (25%) of 169 courses of antibiotic therapy failed to eradicate the organism. 16 (19%) of 85 individuals treated with intramuscular benzathine penicillin G and 9 (19%) of 47 patients treated with an oral antibiotic (penicillin V or erythromycin) continued to harbour the same serotype of group A streptococcus. 12 (48%) of 25 persons remained treatment failures after re-treatment; even after a third course of treatment 5 of 12 (42%) still harboured the organism. Neither antibiotic resistance of the epidemic strain nor reacquisition of the organism from contacts could be implicated as causes. The data suggest that many who did not respond to treatment were streptococcal carriers and raise the possibility that it is more difficult to eradicate the organism from the carrier than from the acutely infected individual.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0140-6736
pubmed:author
pubmed:issnType
Print
pubmed:day
6
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
498-502
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Failure of penicillin to eradicate group A streptococci during an outbreak of pharyngitis.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.