Linked Life Data

6102942

Source:http://linkedlifedata.com/resource/pubmed/id/6102942

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1980-7-22
pubmed:abstractText
The possible implication of the beta-sympathoadrenergic system in regulating the rhythmicity of the renin-angiotensin-aldosterone system (RAAS) was studied in ten normotensive volunteers and in thirty-nine essential hypertensive patients. The study was carried out by simultaneous radioimmunological measurements of diurnal levels of plasma renin and aldosterone before and during acute oral medication of beta-adrenoceptors with propranolol. Acute beta-blockade was seen to blunt the circadian periodicity of plasma renin and aldosterone in normotensives and in hypertensives with normal or high renin patterns. Conversely propranolol was seen to be ineffective in low-renin patients. The disappearance of the circadian rhythms under beta-adrenoceptor blockade tends to suggest the existence of a beta-adrenergic control of RAAS cyclicity in normal condition, as well as in normal or high renin essential hypertension. The inefficacy of propranolol in hyporeninemic hypertensives is consistent with the hypothesis that low-renin essemtoa; juertemsopm os a state in which the sympatho beta-adrenergic mechanism controlling the function of RAAS has no biologic time structure.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0046-5968
pubmed:author
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
184-90
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1980
pubmed:articleTitle
Beta-adrenergic regulation of circadian rhythmicity of the renin-angiotensin-aldosterone system in five subtypes of essential hypertension.
pubmed:publicationType
Journal Article