Linked Life Data

6097643

Source:http://linkedlifedata.com/resource/pubmed/id/6097643

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1985-2-28
pubmed:abstractText
Aplysia neurons grown in primary cell culture (Dagan and Levitan, 1981) were exposed to the putative neurotransmitters acetylcholine and serotonin by local iontophoretic application, and changes in membrane potential or voltage clamp currents were examined. It was found that 47% of the neurons were sensitive to cholinergic agonists, 14% to serotonin, and 9% responded to both. Responses could be recorded upon application of the transmitters to the cell bodies as well as along the regenerated neurites. An identified group of neurons, the neurosecretory bag cells, exhibited similar responses to cholinergic agonists in culture and in situ. Pleural medial neurons exhibited cholinergic responses in culture similar to those previously reported in situ. Thus neurotransmitter receptor/ion channel complexes characteristic for a specific cell type in the intact ganglion are also present on this cell type in culture.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0022-3034
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
429-40
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Sensitivity of Aplysia neurons in primary culture to putative neurotransmitters.
pubmed:publicationType
Journal Article, Comparative Study