Linked Life Data

6096545

Source:http://linkedlifedata.com/resource/pubmed/id/6096545

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1985-2-5
pubmed:abstractText
Different tests were performed on 15 young (age between 17 and 39) and 13 older (62-83) subjects. Blood polymorphs and monocytes were separately tested for ingestion of 3 different particle species and stimulation of superoxide anion production. The erythrocyte sedimentation rate and the serum concentrations of 10 proteins possibly related to inflammatory processes were also determined. It is concluded that: Individual variations of phagocyte ability to be stimulated by different cell types are independent processes. Aged people displayed selective decrease of Fc receptor-mediated phagocytosis by granulocytes and possibly selective impairment of nonspecific phagocytosis by monocytes. Further, the IgM level was decreased whereas the IgA, C-reactive protein and erythrocyte sedimentation rate were higher in old people than in young subjects. Correlations were found between the serum concentrations of some protein species and phagocytic function, but further experiments were coincidental (if both parameters were age-related) or revealed some causal link. It is suggested that our procedure provides a simple and reproducible way of testing many independent functions of phagocytic cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0141-2760
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
45-50
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Effect of age on different receptors and functions of phagocytic cells.
pubmed:publicationType
Journal Article, Comparative Study, In Vitro