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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1985-2-11
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pubmed:abstractText |
The effects of unilateral application of GABA (10(-5) M) into thalamic motor nuclei (ventralis medialis-ventralis lateralis, VM-VL) on 5-HT transmission in basal ganglia were investigated in halothane-anaesthetized cats implanted with several push-pull cannulae. The release of [3H]5-HT continuously synthesized from [3H]tryptophan was estimated in both caudate nuclei (CN), both substantia nigrae (SN) and in the dorsal raphe nucleus (DRN). [3H]5-HT release was decreased in the two CN and in the two SN but was enhanced in the DRN when GABA was applied into the VM-VL. These results indicate that thalamic motor nuclei are involved in a bilateral regulation of serotoninergic transmission in the basal ganglia.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
|
pubmed:issn |
0006-8993
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
26
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pubmed:volume |
322
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
297-300
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:6095968-Animals,
pubmed-meshheading:6095968-Basal Ganglia,
pubmed-meshheading:6095968-Cats,
pubmed-meshheading:6095968-Caudate Nucleus,
pubmed-meshheading:6095968-Female,
pubmed-meshheading:6095968-Male,
pubmed-meshheading:6095968-Neural Pathways,
pubmed-meshheading:6095968-Raphe Nuclei,
pubmed-meshheading:6095968-Serotonin,
pubmed-meshheading:6095968-Substantia Nigra,
pubmed-meshheading:6095968-Synaptic Transmission,
pubmed-meshheading:6095968-Thalamic Nuclei,
pubmed-meshheading:6095968-gamma-Aminobutyric Acid
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pubmed:year |
1984
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pubmed:articleTitle |
Role of thalamic motor nuclei in bilateral regulation of serotoninergic transmission in cat basal ganglia.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|