Linked Life Data

6094921

Source:http://linkedlifedata.com/resource/pubmed/id/6094921

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1985-1-14
pubmed:abstractText
Sprague-Dawley rats were treated with dimethylhydrazine (DMH) once a week for three months. After a treatment-free period of five months, they were subjected to minimal colon resection with an end-to-end anastomosis. Autopsy (one year after the discontinuation of DMH treatment, and seven months after surgery) demonstrated anastomotic tumors in 50% of the animals. Conclusions were that the carcinogen had induced genetic changes in the nonmigrating stem cells in the colonic crypts and that the chronic reparative process resulting from surgical trauma may have promoted colonic cells to induce tumors at the suture line.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0022-4790
pubmed:author
pubmed:issnType
Print
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
236-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1984
pubmed:articleTitle
Partial colon resection as a promotor of cancer growth in the rat.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't