Linked Life Data

603326

Source:http://linkedlifedata.com/resource/pubmed/id/603326

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1978-3-21
pubmed:abstractText
The effects of 5-fluorouracil (5-FU), 1,3 bis(2-chloroethyl)-1 nitrosurea (BCNU) and cyclophosphamide on plasma levels of corticosterone, prolactin and thyroid stimulating hormone (TSH) were investigated. All the three drugs produce a remarkable adrenocortical activation but the duration of this effect is different. Hypophysectomized rats do not show any increase of plasma corticosterone levels in response to the considered antineoplastic agents. This may be indicative of an action mediated by adrenocorticotropic hormone (ACTH). The same drugs caused a significant fall of plasma TSH. Also the duration of this effect was different for the three compounds. No relevant modifications of plasma prolactin were observed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0301-4533
pubmed:author
pubmed:issnType
Print
pubmed:volume
230
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
324-9
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Effects of some antineoplastic agents on plasma levels of corticosterone, prolactin and thyroid stimulating hormone.
pubmed:publicationType
Journal Article