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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1976-9-25
|
| pubmed:abstractText |
Normal values of mean cell volume (M.C.V.) and of distribution of single cell volumes (S.C.V.) have been observed in erythrocytes of patients with cystic fibrosis using an electronical particle-volume analyzer (sheath flow detector). From these results a strong defect in red cell salt transport seems improbable. Valinomucin induces shrinking (by increase of K+ permeability) and gramicidin D induces swelling (by increase of Na+ permeability) of normal erythrocytes. Addition of C.F. sweat to normal erythrocytes induces no volume change. From this result no influence of the "C.F. factor" on passive ion permeability is concluded.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0340-6199
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
12
|
| pubmed:volume |
122
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
293-6
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:59666-Cystic Fibrosis,
pubmed-meshheading:59666-Erythrocytes,
pubmed-meshheading:59666-Gramicidin,
pubmed-meshheading:59666-Humans,
pubmed-meshheading:59666-Ion Exchange,
pubmed-meshheading:59666-Permeability,
pubmed-meshheading:59666-Potassium,
pubmed-meshheading:59666-Sodium,
pubmed-meshheading:59666-Sweat,
pubmed-meshheading:59666-Valinomycin
|
| pubmed:year |
1976
|
| pubmed:articleTitle |
Cystic fibrosis: normal volumes of red cells. Model experiments on the pathomechanism of the disease.
|
| pubmed:publicationType |
Journal Article
|