Linked Life Data

589840

Source:http://linkedlifedata.com/resource/pubmed/id/589840

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1978-2-18
pubmed:abstractText
Salivary tissue shows inflammatory changes, atrophy, replacement fibrosis, marked pleomorphism and atypia of the acinar epithelium and oncocytic metaplasia in the months following irradiation. The ductular epithelium undergoes squamous changes and within the ductular lumina, secretions become inspissated. The underlying pathogenetic mechanisms for these late irradiation induced changes may be the combination of a direct irradiation effect on acinar epithelium in association with post-obstructive inflammation and ischaemia, secondary to irradiation-induced endarteritis; however, these morphological changes observed may only be the result of an unusual repair phenomenon that salivary tissue is known to go through after any form of noxious stimulation. These histological alterations may lead to a possible misdiagnosis of malignancy in surgical specimens.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0307-7772
pubmed:author
pubmed:issnType
Print
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
199-206
pubmed:dateRevised
2005-5-2
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
Irradiation-induced changes in human salivary glands.
pubmed:publicationType
Journal Article