The gem effect. 3. The influence of 3-mono- and 3-gem substitution on the acid dissociation constants of glutaric acid. A comparison of the sensitivity of delta-pK-a of dicarboxylic acids and the rate of ring closure of their monoesters to the intramolecular distance separating carboxyl functions.
Source:http://linkedlifedata.com/resource/pubmed/id/5844460
J. Am. Chem. Soc.
1965
Nov
5
87
21
4851-5
